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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL49932
Molecular formula	C22H21N5O2
IUPAC name	7-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
Molecular weight	387.443
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.7
Synonyms	BDBM50408168 SCHEMBL8564383
Inchi Key	AZJGEHAZLNOBGW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H21N5O2/c1-3-17-21(23-7-1)27-8-2-4-18(27)22(24-17)26-11-9-25(10-12-26)14-16-5-6-19-20(13-16)29-15-28-19/h1-8,13H,9-12,14-15H2
PubChem CID	10548259
ChEMBL	CHEMBL49932
IUPHAR	N/A
BindingDB	50408168
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18207	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
18211	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
18209	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
18210	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
18208	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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