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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL52800
Molecular formula	C22H22FN5O
IUPAC name	7-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-12-methoxy-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaene
Molecular weight	391.45
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.3
Synonyms	BDBM50408156 SCHEMBL8565934
Inchi Key	ARCIIEQRTPPAQU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22FN5O/c1-29-20-9-8-18-21(25-20)28-10-2-3-19(28)22(24-18)27-13-11-26(12-14-27)15-16-4-6-17(23)7-5-16/h2-10H,11-15H2,1H3
PubChem CID	10715484
ChEMBL	CHEMBL52800
IUPHAR	N/A
BindingDB	50408156
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12301	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
12304	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
12303	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
12302	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
12300	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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