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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL279646
Molecular formula	C25H30FN5O2
IUPAC name	3-(5-fluoro-1H-indol-3-yl)-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]pyrrolidine-1-carboxamide
Molecular weight	451.546
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.1
Synonyms	N-[3-(4-Methylpiperazino)-4-methoxyphenyl]-3-(5-fluoro-1H-indole-3-yl)pyrrolidine-1-carboxamide 3-(5-Fluoro-1H-indol-3-yl)-pyrrolidine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide BDBM50086110
Inchi Key	BMVCAMBJKNURKZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30FN5O2/c1-29-9-11-30(12-10-29)23-14-19(4-6-24(23)33-2)28-25(32)31-8-7-17(16-31)21-15-27-22-5-3-18(26)13-20(21)22/h3-6,13-15,17,27H,7-12,16H2,1-2H3,(H,28,32)
PubChem CID	10647243
ChEMBL	CHEMBL279646
IUPHAR	N/A
BindingDB	50086110
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27799	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
27797	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
27798	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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