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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL303986
Molecular formula	C19H23N5OS
IUPAC name	1-pyrrolidin-1-yl-2-[4-(3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaen-8-yl)piperazin-1-yl]ethanone
Molecular weight	369.487
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM50407763 SCHEMBL7298957
Inchi Key	BGPSOKRQZWMDEI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23N5OS/c25-17(22-6-1-2-7-22)14-21-9-11-23(12-10-21)18-16-4-3-8-24(16)19-15(20-18)5-13-26-19/h3-5,8,13H,1-2,6-7,9-12,14H2
PubChem CID	10737848
ChEMBL	CHEMBL303986
IUPHAR	N/A
BindingDB	50407763
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23286	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
23288	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
23284	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
23287	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
23285	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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