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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL28178
Molecular formula	C16H15F3N4
IUPAC name	4-piperazin-1-yl-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
Molecular weight	320.319
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.5
Synonyms	4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline 7-Trifluoromethyl-4-(1-piperazinyl)pyrrolo[1,2-a]quinoxaline 4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline(desmethyl-CGS-12066B) BDBM50015710
Inchi Key	BLPNNGLJLMTUHN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H15F3N4/c17-16(18,19)11-3-4-13-12(10-11)21-15(14-2-1-7-23(13)14)22-8-5-20-6-9-22/h1-4,7,10,20H,5-6,8-9H2
PubChem CID	10805623
ChEMBL	CHEMBL28178
IUPHAR	N/A
BindingDB	50015710
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
26874	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
26875	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
26873	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
26872	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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