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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL274922
Molecular formula	C27H34N6O3
IUPAC name	3-[1-[[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]carbamoyl]piperidin-4-yl]-1H-indole-5-carboxamide
Molecular weight	490.608
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.3
Synonyms	SCHEMBL6345386 3-{1-[4-Methoxy-3-(4-methyl-piperazin-1-yl)-phenylcarbamoyl]-piperidin-4-yl}-1H-indole-5-carboxylic acid amide 3-[1-[[3-(4-Methylpiperazino)-4-methoxyphenyl]carbamoyl]piperidine-4-yl]-1H-indole-5-carboxamide BDBM50086095
Inchi Key	BWSZPXLKWNGQFZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H34N6O3/c1-31-11-13-32(14-12-31)24-16-20(4-6-25(24)36-2)30-27(35)33-9-7-18(8-10-33)22-17-29-23-5-3-19(26(28)34)15-21(22)23/h3-6,15-18,29H,7-14H2,1-2H3,(H2,28,34)(H,30,35)
PubChem CID	10529106
ChEMBL	CHEMBL274922
IUPHAR	N/A
BindingDB	50086095
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
34707	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
34709	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
34708	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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