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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL410531
Molecular formula	C22H20ClFN4
IUPAC name	7-chloro-4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]pyrrolo[1,2-a]quinoxaline
Molecular weight	394.878
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.3
Synonyms	SCHEMBL8571686 BDBM50408175
Inchi Key	BUOWEEIISDGZDM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H20ClFN4/c23-17-5-8-20-19(14-17)25-22(21-2-1-9-28(20)21)27-12-10-26(11-13-27)15-16-3-6-18(24)7-4-16/h1-9,14H,10-13,15H2
PubChem CID	10620679
ChEMBL	CHEMBL410531
IUPHAR	N/A
BindingDB	50408175
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33237	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
33235	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
33236	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
33238	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
33239	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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