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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL133375
Molecular formula	C28H40N2O4
IUPAC name	8-[4-(1'-propylspiro[2,4-dihydrochromene-3,2'-pyrrolidine]-5-yl)oxybutyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular weight	468.638
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.9
Synonyms	BDBM50054155 SCHEMBL8556860 8-[4-[[1'-Propylspiro[2H-1-benzopyran-3(4H),2'-pyrrolidin]-5-yl]oxy]butyl]-8-azaspiro[4.5]decane-7,9-dione 8-{4-[1''-propylspiro[3,4-dihydro-2H-chromene-3,2''-(tetrahydro-1''H-pyrrole)]-5-yloxy]butyl}-8-azaspiro[4.5]decane-7,9-dione
Inchi Key	CVBMSXGNWVNTDT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H40N2O4/c1-2-14-29-15-8-13-28(29)18-22-23(9-7-10-24(22)34-21-28)33-17-6-5-16-30-25(31)19-27(20-26(30)32)11-3-4-12-27/h7,9-10H,2-6,8,11-21H2,1H3
PubChem CID	10838030
ChEMBL	CHEMBL133375
IUPHAR	N/A
BindingDB	50054155
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51346	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
51345	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386

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