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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL53662
Molecular formula	C23H23FN4O
IUPAC name	4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-7-methoxypyrrolo[1,2-a]quinoxaline
Molecular weight	390.462
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.7
Synonyms	BDBM50408152 SCHEMBL8565546
Inchi Key	ACSDLURGGYXLSE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H23FN4O/c1-29-19-8-9-21-20(15-19)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-17-4-6-18(24)7-5-17/h2-10,15H,11-14,16H2,1H3
PubChem CID	10452995
ChEMBL	CHEMBL53662
IUPHAR	N/A
BindingDB	50408152
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1867	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
1866	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
1864	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
1865	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
1868	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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