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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	S 14489
Molecular formula	C22H26N2O2
IUPAC name	1-[2-(7-bicyclo[4.2.0]octa-1,3,5-trienyl)ethyl]-4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine
Molecular weight	350.462
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.3
Synonyms	4-(Benzodioxan-5-yl)-1-(2-(benzocyclobutan-1-yl)ethyl)piperazine CTK4C7917 S-14489 ACMC-20n6r7 PDSP1_000558 1-[2-(7-bicyclo[4.2.0]octa-1,3,5-trienyl)ethyl]-4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine Piperazine,1-(2-bicyclo[4.2.0]octa-1,3,5-trien-7-ylethyl)-4-(2,3-dihydro-1,4-benzodioxin-5-yl)- L006788 SCHEMBL1037297 BDBM82562 PDSP2_000556 153607-44-4 CHEMBL130276 AC1L4BA2 NSC_182595 CAS_182595 Piperazine, 1-(2-bicyclo(4.2.0)octa-1,3,5-trien-7-ylethyl)-4-(2,3-dihydro-1,4-benzodioxin-5-yl)- [ Show all ]
Inchi Key	DHYRQVXQZAGWKI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N2O2/c1-2-5-19-17(4-1)16-18(19)8-9-23-10-12-24(13-11-23)20-6-3-7-21-22(20)26-15-14-25-21/h1-7,18H,8-16H2
PubChem CID	182595
ChEMBL	CHEMBL130276
IUPHAR	N/A
BindingDB	82562
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
60492	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
60494	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
60493	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
555707	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
60491	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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