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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL364005
Molecular formula	C14H15ClN2
IUPAC name	5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Molecular weight	246.738
Hydrogen bond acceptor	1
Hydrogen bond donor	2
XlogP	2.8
Synonyms	EMD386088 A830276 D0G7QT SCHEMBL1548928 5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole BRD-K47659338-003-01-0 EMD-386,088 54635-62-0 GTPL8428 5-chloranyl-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole AKOS023409828 DTXSID30436055 ZINC9350 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole CHEBI:92829 EMD-386088 compound 18 [PMID 16055331] NCGC00161402-01 5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole BDBM50171235 EMD 386088 [ Show all ]
Inchi Key	BPPGPYJBCVXILI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H15ClN2/c1-9-14(10-4-6-16-7-5-10)12-8-11(15)2-3-13(12)17-9/h2-4,8,16-17H,5-7H2,1H3
PubChem CID	10131112
ChEMBL	CHEMBL364005
IUPHAR	8428
BindingDB	50171235
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29761	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
29765	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
29767	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
29764	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
29766	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
29763	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
29760	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
29762	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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