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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL66307
Molecular formula	C26H23ClN4S
IUPAC name	8-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene
Molecular weight	459.008
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	7.0
Synonyms	SCHEMBL7296930 BDBM50407776
Inchi Key	DFXLNCRNORESIF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H23ClN4S/c27-21-10-8-20(9-11-21)24(19-5-2-1-3-6-19)29-14-16-30(17-15-29)25-23-7-4-13-31(23)26-22(28-25)12-18-32-26/h1-13,18,24H,14-17H2
PubChem CID	10718731
ChEMBL	CHEMBL66307
IUPHAR	N/A
BindingDB	50407776
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59002	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
59000	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
58998	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
58999	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
59001	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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