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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2376491
Molecular formula	C20H20N2
IUPAC name	2-methyl-5-phenyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Molecular weight	288.394
Hydrogen bond acceptor	1
Hydrogen bond donor	2
XlogP	3.8
Synonyms	N/A
Inchi Key	CWYJMCYDDSRPBB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N2/c1-14-20(16-9-11-21-12-10-16)18-13-17(7-8-19(18)22-14)15-5-3-2-4-6-15/h2-9,13,21-22H,10-12H2,1H3
PubChem CID	73351905
ChEMBL	CHEMBL2376491
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52583	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
52586	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
52584	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
52582	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
52585	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
52587	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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