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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL11787
Molecular formula	C26H32N2O4
IUPAC name	8-[4-(2,3-dihydrobenzo[f][1,4]benzodioxin-3-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular weight	436.552
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	BDBM50421838
Inchi Key	CPZXZWSBPRKTEA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H32N2O4/c29-23-15-26(11-3-4-12-26)16-24(30)28(23)14-6-5-13-27-17-20-18-31-25-21-8-2-1-7-19(21)9-10-22(25)32-20/h1-2,7-10,20,27H,3-6,11-18H2
PubChem CID	44267852
ChEMBL	CHEMBL11787
IUPHAR	N/A
BindingDB	50421838
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
47862	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
47861	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
47863	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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