Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
519706	SCHEMBL1615993	C23H29NO4S	415.548	5 / 1	4.3	Yes
519715	SCHEMBL1278876	C23H28N2O5S	444.546	6 / 2	2.7	Yes
519728	MLS000092301	C18H17N3O6S	403.409	7 / 1	1.0	Yes
519736	CHEMBL3092263	C22H27NO5S	417.52	6 / 1	4.4	Yes
519752	SCHEMBL1279663	C16H10N4O2S	322.342	6 / 1	3.2	Yes
519760	SCHEMBL1279268	C22H27NO4S	401.521	5 / 1	3.9	Yes
519766	4-(dibenzylsulfamoyl)benzoic Acid	C21H19NO4S	381.446	5 / 1	3.6	Yes
519768	872621-06-2	C16H20N4O3S	348.421	6 / 0	1.7	Yes
519786	N-cyclohexyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide	C16H21N3O4S	351.421	5 / 1	1.6	Yes
519814	SCHEMBL1279135	C22H26FNO4S	419.511	6 / 1	3.6	Yes
519845	(Z)-3-(5-(2,5-dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid	C15H15NO5S2	353.407	7 / 1	2.4	Yes
519857	SCHEMBL1278988	C19H22FNO4S2	411.506	7 / 1	3.7	Yes
519870	Oprea1_826406	C23H28BrNO4S	494.444	5 / 0	4.9	Yes
519890	SCHEMBL1279307	C21H18FNO5S	415.435	7 / 2	3.3	Yes
519896	SCHEMBL1279537	C14H19N5O3S	337.398	6 / 0	0.6	Yes
519929	MLS001126395	C17H16FN3O4S	377.39	6 / 1	1.8	Yes
519961	SCHEMBL1279003	C21H24FNO4S	405.484	6 / 1	3.7	Yes
519966	SCHEMBL1279380	C22H20FNO5S	429.462	7 / 1	3.7	Yes
520035	SCHEMBL1279440	C22H23NO4S	397.489	5 / 0	4.0	Yes
445091	GSK137647A	C16H19NO3S	305.392	4 / 1	3.5	Yes
520075	AC1NDBVX	C24H29ClN2O2S	445.018	3 / 2	5.6	No
520080	N-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide	C9H9N3O4S	255.248	5 / 3	-0.6	Yes
520088	Oprea1_594647	C23H28ClNO4S	449.99	5 / 0	4.9	Yes
520113	SCHEMBL1279688	C21H20N2O5S	412.46	7 / 1	2.8	Yes
520116	Oprea1_513452	C20H19NO6S	401.433	7 / 1	2.7	Yes
520119	SCHEMBL1615032	C21H18FNO4S	399.436	6 / 1	3.7	Yes
520131	SCHEMBL1279598	C23H20N2O5S	436.482	7 / 1	3.3	Yes
538574	SCHEMBL1279804	C23H23NO5S	425.499	6 / 1	4.0	Yes
520148	4-[((4-methoxybenzyl){[(2-methoxyphenyl)amino]carbonothioyl}amino)methyl]cyclohexanecarboxylic acid	C24H30N2O4S	442.574	5 / 2	4.1	Yes
520163	SCHEMBL1278748	C22H21NO6S	427.471	7 / 2	3.2	Yes
520172	SCHEMBL1279013	C22H19NO6S	425.455	7 / 1	3.4	Yes
520260	Oprea1_386690	C25H32N2O5S	472.6	6 / 1	3.4	Yes
520272	SCHEMBL1279325	C22H20FNO4S	413.463	6 / 1	4.0	Yes
520273	AC1NSIFU	C18H25N5O3S	391.49	6 / 0	1.9	Yes
520325	SCHEMBL1279102	C22H19NO5S	409.456	6 / 1	3.3	Yes
520326	SCHEMBL1279249	C22H21NO4S2	427.533	6 / 1	4.1	Yes
520330	SCHEMBL1279479	C21H18FNO4S	399.436	6 / 1	3.7	Yes
540088	SCHEMBL1279010	C25H25NO5S	451.537	6 / 1	4.3	Yes
520365	SCHEMBL1279106	C23H23NO6S	441.498	7 / 1	3.5	Yes
520377	N-(3-fluoro-2-methylphenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide	C17H16FN3O4S	377.39	6 / 1	1.8	Yes
520402	SCHEMBL1279120	C21H19NO5S	397.445	6 / 2	3.2	Yes
520406	SCHEMBL1279662	C22H20ClNO5S	445.914	6 / 1	4.2	Yes
520408	SCHEMBL1279439	C22H21NO4S	395.473	5 / 1	3.9	Yes
520422	SCHEMBL1279628	C19H12N4O3S	376.39	7 / 1	3.9	Yes
520432	SCHEMBL1279660	C21H18ClNO4S	415.888	5 / 1	4.2	Yes
520462	SCHEMBL1279764	C22H21NO6S	427.471	7 / 2	3.2	Yes
520477	SCHEMBL1279497	C23H23NO4S	409.5	5 / 1	4.4	Yes
520491	SCHEMBL1279183	C22H21NO4S	395.473	5 / 1	3.9	Yes
520492	AC1NLP7L	C18H17N3O6S	403.409	7 / 1	1.0	Yes
520493	SCHEMBL1279528	C22H23NO6S	429.487	7 / 1	3.6	Yes
520494	SMR000081775	C17H15N3O6S	389.382	7 / 1	1.1	Yes
520511	SCHEMBL1279684	C25H32N2O2S	424.603	3 / 2	5.4	No
520522	UNM000000883401	C24H30ClNO4S	464.017	5 / 0	5.2	No
520523	Oprea1_014947	C19H17NO5S	371.407	6 / 1	2.7	Yes
520535	AC1OMQJ3	C18H18N4O3S	370.427	5 / 1	1.4	Yes
520537	SCHEMBL1279321	C22H19F2NO5S	447.453	8 / 1	3.8	Yes
520538	CHEMBL3092287	C22H21NO5S	411.472	6 / 1	3.6	Yes
520544	Oprea1_007249	C21H21NO6S	415.46	7 / 1	3.0	Yes
520567	SCHEMBL1279638	C22H20ClNO5S	445.914	6 / 1	4.2	Yes
520583	SCHEMBL1279068	C23H22FNO6S	459.488	8 / 1	3.6	Yes
520603	AC1NT3IW	C25H30BrNO6S	552.48	7 / 0	4.7	No
520623	SCHEMBL1615515	C21H18FNO4S	399.436	6 / 1	3.7	Yes
520634	SCHEMBL1615156	C16H13ClFN3O4S	397.805	6 / 1	2.1	Yes
520650	SCHEMBL1279146	C16H17NO6S2	383.433	8 / 1	2.4	Yes
520657	SCHEMBL1278774	C22H18N2O4S	406.456	6 / 1	3.3	Yes
520662	SCHEMBL1279288	C17H19NO5S	349.401	6 / 1	2.4	Yes
520672	SCHEMBL1279232	C23H22FNO6S	459.488	8 / 1	3.6	Yes
520679	SCHEMBL1616132	C21H25FN2O4S	420.499	7 / 2	3.0	Yes
520690	SCHEMBL1279599	C20H23FN2O4S	406.472	7 / 1	2.6	Yes
520710	SCHEMBL1278727	C23H23NO6S	441.498	7 / 1	3.5	Yes
520749	Oprea1_395930	C22H26FNO5S	435.51	7 / 1	3.6	Yes
520764	SCHEMBL1279410	C22H18N2O4S	406.456	6 / 1	3.3	Yes
543408	SCHEMBL1279284	C23H21NO5S	423.483	6 / 1	3.6	Yes
520795	SCHEMBL1615022	C22H21NO5S	411.472	6 / 1	3.6	Yes
520798	SCHEMBL1278766	C23H23NO5S	425.499	6 / 1	3.9	Yes
520811	N-(2,3-dimethylquinoxalin-6-yl)-1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide	C20H19N5O4S	425.463	7 / 1	1.4	Yes
520815	1,4-dimethyl-2,3-dioxo-N-[4-(pyridin-2-ylmethyl)phenyl]-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide	C22H20N4O4S	436.486	6 / 1	2.2	Yes
520816	SCHEMBL1278600	C22H21NO5S	411.472	6 / 1	3.6	Yes
520829	SCHEMBL1279324	C21H18ClNO4S	415.888	5 / 1	4.2	Yes
520881	SCHEMBL1279128	C21H18FNO4S	399.436	6 / 1	3.7	Yes
520894	SCHEMBL1615513	C22H21NO5S	411.472	6 / 1	3.6	Yes
520906	SCHEMBL1278916	C22H21NO6S	427.471	7 / 2	3.2	Yes
520909	4-Diisobutylsulfamoyl-benzoic acid	C15H23NO4S	313.412	5 / 1	4.1	Yes
544582	SCHEMBL1279151	C23H21NO5S	423.483	6 / 1	3.8	Yes
520958	SCHEMBL1279014	C23H23NO6S	441.498	7 / 1	3.5	Yes
520960	SCHEMBL1615476	C23H27FN2O5S	462.536	7 / 2	2.8	Yes
520966	SCHEMBL1279785	C23H23NO5S	425.499	6 / 1	3.9	Yes
520982	SCHEMBL1279561	C24H25NO7S	471.524	8 / 1	3.5	Yes
520994	Oprea1_056229	C22H26FNO4S	419.511	6 / 1	4.0	Yes
520996	AC1LT76E	C19H18N4O4S	398.437	6 / 1	2.3	Yes
521007	SCHEMBL1615817	C21H18FNO4S	399.436	6 / 1	3.7	Yes
521032	SCHEMBL1615504	C23H29NO5S	431.547	6 / 1	3.9	Yes
521035	SCHEMBL1278819	C20H19NO6S	401.433	7 / 1	2.7	Yes
521038	1,3-dimethyl-N-(2-methylphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide	C17H17N3O4S	359.4	5 / 1	1.7	Yes
521041	SCHEMBL1615502	C23H26N2O4S	426.531	6 / 1	3.6	Yes
521048	SCHEMBL1279372	C23H23NO6S	441.498	7 / 1	3.5	Yes
521056	4-{[{[(3-chloro-4-methylphenyl)amino]carbonothioyl}(4-methoxybenzyl)amino]methyl}cyclohexanecarboxylic acid	C24H29ClN2O3S	461.017	4 / 2	5.2	No
521061	899748-38-0	C17H22N4O3S	362.448	5 / 0	1.3	Yes
521087	1,3,7-trimethyl-5-((2-oxo-2-(piperidin-1-yl)ethyl)thio)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione	C16H21N5O3S	363.436	6 / 0	1.0	Yes
521096	AC1NESFS	C15H19N5O4S	365.408	7 / 0	-0.2	Yes

zhanglab

zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417