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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Oprea1_014947
Molecular formula	C19H17NO5S
IUPAC name	4-[benzyl(furan-2-ylmethyl)sulfamoyl]benzoic acid
Molecular weight	371.407
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.7
Synonyms	4-(N-benzyl-N-(furan-2-ylmethyl)sulfamoyl)benzoic acid CHEMBL3932685 SCHEMBL1279234 BDBM211084 MGRFWMNQLHWSGX-UHFFFAOYSA-N US9247759, 5-5 [ Show all ]
Inchi Key	MGRFWMNQLHWSGX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H17NO5S/c21-19(22)16-8-10-18(11-9-16)26(23,24)20(14-17-7-4-12-25-17)13-15-5-2-1-3-6-15/h1-12H,13-14H2,(H,21,22)
PubChem CID	24134643
ChEMBL	CHEMBL3932685
IUPHAR	N/A
BindingDB	211084
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	4600.0 nM	N/A	BindingDB
IC50	4600.0 nM	None	ChEMBL

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