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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL1279128
Molecular formula	C21H18FNO4S
IUPAC name	4-[benzyl-[(2-fluorophenyl)methyl]sulfamoyl]benzoic acid
Molecular weight	399.436
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.7
Synonyms	US9247759, 5-134 CHEMBL3962533 US9247759, 5-72 BDBM211140
Inchi Key	RSRNGNJRMKTOEE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H18FNO4S/c22-20-9-5-4-8-18(20)15-23(14-16-6-2-1-3-7-16)28(26,27)19-12-10-17(11-13-19)21(24)25/h1-13H,14-15H2,(H,24,25)
PubChem CID	57422365
ChEMBL	CHEMBL3962533
IUPHAR	N/A
BindingDB	211140
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	6164.0 nM	None	ChEMBL
IC50	6164.0 nM	N/A	BindingDB

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