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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-{[{[(3-chloro-4-methylphenyl)amino]carbonothioyl}(4-methoxybenzyl)amino]methyl}cyclohexanecarboxylic acid
Molecular formula	C24H29ClN2O3S
IUPAC name	4-[[(3-chloro-4-methylphenyl)carbamothioyl-[(4-methoxyphenyl)methyl]amino]methyl]cyclohexane-1-carboxylic acid
Molecular weight	461.017
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.2
Synonyms	SR-01000582762 BDBM211165 HMS2698K18 ZINC3036022 SCHEMBL1649775 AC1N2R2O SR-01000582762-1 MLS000673573 4-[[(3-chloro-4-methylphenyl)carbamothioyl-[(4-methoxyphenyl)methyl]amino]methyl]cyclohexane-1-carboxylic acid SMR000314814 AKOS002117272 US9247759, 5-111 CHEMBL1323541 MolPort-007-929-133 [ Show all ]
Inchi Key	UWOJQANBRFCVCC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29ClN2O3S/c1-16-3-10-20(13-22(16)25)26-24(31)27(15-18-6-11-21(30-2)12-7-18)14-17-4-8-19(9-5-17)23(28)29/h3,6-7,10-13,17,19H,4-5,8-9,14-15H2,1-2H3,(H,26,31)(H,28,29)
PubChem CID	4075726
ChEMBL	CHEMBL1323541
IUPHAR	N/A
BindingDB	211165
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
347507	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
521056	Taste receptor type 2 member 14	Q9NYV8	TAS2R14	Homo sapiens (Human)	317

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