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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL1279528
Molecular formula	C22H23NO6S
IUPAC name	4-[furan-2-ylmethyl-[(4-propoxyphenyl)methyl]sulfamoyl]benzoic acid
Molecular weight	429.487
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.6
Synonyms	BDBM211087 US9247759, 5-8 CHEMBL3895732
Inchi Key	LWIJOTQNQDTITE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H23NO6S/c1-2-13-28-19-9-5-17(6-10-19)15-23(16-20-4-3-14-29-20)30(26,27)21-11-7-18(8-12-21)22(24)25/h3-12,14H,2,13,15-16H2,1H3,(H,24,25)
PubChem CID	25206327
ChEMBL	CHEMBL3895732
IUPHAR	N/A
BindingDB	211087
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2500.0 nM	N/A	BindingDB
IC50	2500.0 nM	None	ChEMBL

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