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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	AC1NT3IW
Molecular formula	C25H30BrNO6S
IUPAC name	ethyl 4-[[(3-bromophenyl)methyl-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]methyl]cyclohexane-1-carboxylate
Molecular weight	552.48
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	4.7
Synonyms	CHEMBL3900023 UNM000000887501 EU-0063632 BDBM211170 SR-01000582810 ethyl 4-[[(3-bromophenyl)methyl-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]methyl]cyclohexane-1-carboxylate US9247759, 5-116 MolPort-007-929-176 SR-01000582810-1 ethyl 4-{[(3-bromobenzyl)(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]methyl}cyclohexanecarboxylate ZINC98009716 AKOS002116364 SCHEMBL1615828 [ Show all ]
Inchi Key	NPEHVZUAWFRIBL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30BrNO6S/c1-2-31-25(28)20-8-6-18(7-9-20)16-27(17-19-4-3-5-21(26)14-19)34(29,30)22-10-11-23-24(15-22)33-13-12-32-23/h3-5,10-11,14-15,18,20H,2,6-9,12-13,16-17H2,1H3
PubChem CID	5323300
ChEMBL	CHEMBL3900023
IUPHAR	N/A
BindingDB	211170
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2567.0 nM	None	ChEMBL
IC50	2567.0 nM	N/A	BindingDB

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