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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Oprea1_826406
Molecular formula	C23H28BrNO4S
IUPAC name	ethyl 4-[[benzyl-(4-bromophenyl)sulfonylamino]methyl]cyclohexane-1-carboxylate
Molecular weight	494.444
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.9
Synonyms	MolPort-007-926-081 SCHEMBL1615797 HMS1912B04 US9247759, 5-118 AKOS002126271 NCGC00139288-01 CHEMBL1434982 SR-01000579847 K783-1137 ZINC8583119 BDBM211172 ethyl 4-({benzyl[(4-bromophenyl)sulfonyl]amino}methyl)cyclohexanecarboxylate SR-01000579847-1 [ Show all ]
Inchi Key	CDTBMPSOZQXMBI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28BrNO4S/c1-2-29-23(26)20-10-8-19(9-11-20)17-25(16-18-6-4-3-5-7-18)30(27,28)22-14-12-21(24)13-15-22/h3-7,12-15,19-20H,2,8-11,16-17H2,1H3
PubChem CID	16034014
ChEMBL	CHEMBL1434982
IUPHAR	N/A
BindingDB	211172
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2344.0 nM	None	ChEMBL
IC50	2344.0 nM	N/A	BindingDB

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