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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL1279014
Molecular formula	C23H23NO6S
IUPAC name	4-[(2-methoxyphenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acid
Molecular weight	441.498
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.5
Synonyms	US9247759, 5-121 CHEMBL3892212 US9247759, 5-58 BDBM211134
Inchi Key	SUXWUHBVGUAFSJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H23NO6S/c1-29-20-11-7-17(8-12-20)15-24(16-19-5-3-4-6-22(19)30-2)31(27,28)21-13-9-18(10-14-21)23(25)26/h3-14H,15-16H2,1-2H3,(H,25,26)
PubChem CID	57422352
ChEMBL	CHEMBL3892212
IUPHAR	N/A
BindingDB	211134
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2943.0 nM	None	ChEMBL
IC50	2943.0 nM	N/A	BindingDB

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