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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL1279068
Molecular formula	C23H22FNO6S
IUPAC name	4-[(4-fluoro-3-methoxyphenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acid
Molecular weight	459.488
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.6
Synonyms	US9247759, 5-50 CHEMBL3946037 BDBM211126
Inchi Key	NFUHADOILDJEGX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22FNO6S/c1-30-19-8-3-16(4-9-19)14-25(15-17-5-12-21(24)22(13-17)31-2)32(28,29)20-10-6-18(7-11-20)23(26)27/h3-13H,14-15H2,1-2H3,(H,26,27)
PubChem CID	57944972
ChEMBL	CHEMBL3946037
IUPHAR	N/A
BindingDB	211126
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1650.0 nM	N/A	BindingDB
IC50	1650.0 nM	None	ChEMBL

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