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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL1279321
Molecular formula	C22H19F2NO5S
IUPAC name	4-[(2,4-difluorophenyl)methyl-[(4-methoxyphenyl)methyl]sulfamoyl]benzoic acid
Molecular weight	447.453
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.8
Synonyms	US9247759, 5-160 CHEMBL3940903 BDBM211213
Inchi Key	MNGGCNGLUSIXIG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H19F2NO5S/c1-30-19-8-2-15(3-9-19)13-25(14-17-4-7-18(23)12-21(17)24)31(28,29)20-10-5-16(6-11-20)22(26)27/h2-12H,13-14H2,1H3,(H,26,27)
PubChem CID	57422405
ChEMBL	CHEMBL3940903
IUPHAR	N/A
BindingDB	211213
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1255.0 nM	N/A	BindingDB
IC50	1255.0 nM	None	ChEMBL

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