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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Taste receptor type 2 member 14
Species	Homo sapiens (Human)
Gene	TAS2R14
Synonym	T2R14 TAS2R14 Taste receptor family B member 1 taste receptor, type 2, member 14 TRB1
Disease	N/A
Length	317
Amino acid sequence	MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
UniProt	Q9NYV8
Protein Data Bank	N/A
GPCR-HGmod model	Q9NYV8
3D structure model	This predicted structure model is from GPCR-EXP Q9NYV8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3309105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL1279660
Molecular formula	C21H18ClNO4S
IUPAC name	4-[benzyl-[(3-chlorophenyl)methyl]sulfamoyl]benzoic acid
Molecular weight	415.888
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	US9247759, 5-142 CHEMBL3952395 US9247759, 5-84 BDBM211148
Inchi Key	KXWPZVUAGUOJMF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H18ClNO4S/c22-19-8-4-7-17(13-19)15-23(14-16-5-2-1-3-6-16)28(26,27)20-11-9-18(10-12-20)21(24)25/h1-13H,14-15H2,(H,24,25)
PubChem CID	57422375
ChEMBL	CHEMBL3952395
IUPHAR	N/A
BindingDB	211148
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	4286.0 nM	N/A	BindingDB
IC50	4286.0 nM	None	ChEMBL

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