You can:
Name | Platelet-activating factor receptor |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Ptafr |
Synonym | AGEPC receptor PAF receptor PAF-R PAFr |
Disease | N/A for non-human GPCRs |
Length | 341 |
Amino acid sequence | MEQNGSFRVDSEFRYTLFPIVYSVIFVLGVVANGYVLWVFATLYPSKKLNEIKIFMVNLTVADLLFLMTLPLWIVYYSNEGDWIVHKFLCNLAGCLFFINTYCSVAFLGVITYNRYQAVAYPIKTAQATTRKRGITLSLVIWISIAATASYFLATDSTNVVPKKDGSGNITRCFEHYEPYSVPILVVHIFITSCFFLVFFLIFYCNMVIIHTLLTRPVRQQRKPEVKRRALWMVCTVLAVFVICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFRKHLSEKFYSMRSSRKCSRATSDTCTEVMMPANQTPVLPLKN |
UniProt | P46002 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4127 |
IUPHAR | N/A |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
4049 | CHEMBL51798 | C31H39NO8S2 | 617.772 | 10 / 1 | 5.1 | No |
5414 | CHEMBL418989 | C28H31N5O3S | 517.648 | 7 / 0 | 2.9 | No |
6168 | CHEMBL134025 | C16H22N4O | 286.379 | 4 / 0 | 1.3 | Yes |
6933 | CHEMBL127766 | C36H61NO6S2 | 668.005 | 7 / 0 | N/A | No |
7575 | CHEMBL339676 | C36H59NO6S2 | 665.989 | 7 / 0 | N/A | No |
10832 | CHEMBL3216875 | C27H29Cl2N3O2 | 498.448 | 5 / 2 | N/A | N/A |
11375 | CV-6209 | C34H60ClN3O6 | 642.319 | 7 / 1 | N/A | No |
12794 | CHEMBL174262 | C25H20N4O3 | 424.46 | 5 / 1 | 3.7 | Yes |
14654 | CHEMBL125576 | C33H56ClN3O6 | 626.276 | 8 / 1 | N/A | No |
14863 | CHEMBL318908 | C27H27N5O2 | 453.546 | 6 / 0 | 4.0 | Yes |
18140 | CHEMBL103571 | C28H29N5O2 | 467.573 | 5 / 0 | 3.1 | Yes |
20160 | CHEMBL443811 | C27H44N4O | 440.676 | 4 / 0 | 7.3 | No |
21992 | CHEMBL367418 | C30H30FN5O2 | 511.601 | 5 / 0 | 4.8 | No |
22019 | CHEMBL132028 | C26H34N2O8 | 502.564 | 8 / 0 | 2.4 | No |
25839 | CHEMBL3215984 | C18H20Cl2N4O | 379.285 | 4 / 2 | N/A | N/A |
26734 | CHEMBL103903 | C27H26N4O | 422.532 | 4 / 0 | 4.3 | Yes |
27160 | CHEMBL545072 | C27H30ClN5O | 476.021 | 5 / 1 | N/A | N/A |
27881 | CHEMBL338689 | C32H55IN2O5 | 674.705 | 6 / 0 | N/A | No |
31796 | CHEMBL103561 | C28H31N5O | 453.59 | 5 / 1 | 3.3 | Yes |
33163 | CHEMBL127531 | C24H50NO5P | 463.64 | 5 / 0 | 6.7 | No |
33662 | CHEMBL102070 | C27H28N6O2 | 468.561 | 6 / 1 | 1.7 | Yes |
33881 | CHEMBL173497 | C28H24FN5O2 | 481.531 | 5 / 1 | 3.5 | Yes |
34323 | CHEMBL367673 | C25H27N5O4 | 461.522 | 6 / 0 | 2.6 | Yes |
34965 | CHEMBL102918 | C28H29N5O2 | 467.573 | 5 / 1 | 2.8 | Yes |
35541 | CHEMBL293773 | C31H38O10S2 | 634.755 | 10 / 0 | 4.5 | No |
36382 | CHEMBL1203313 | C22H28ClN5O | 413.95 | 5 / 2 | N/A | N/A |
36645 | CHEMBL125078 | C36H61NO5S2 | 652.006 | 6 / 0 | N/A | No |
37975 | CHEMBL542731 | C26H29ClN4 | 432.996 | 4 / 1 | N/A | N/A |
38160 | CHEMBL368292 | C30H24N4O2 | 472.548 | 4 / 1 | 5.3 | No |
40244 | CHEMBL318163 | C24H27N5O3 | 433.512 | 6 / 0 | 1.5 | Yes |
41305 | CHEMBL555567 | C26H30ClN5 | 448.011 | 5 / 2 | N/A | N/A |
41647 | CHEMBL132824 | C26H26N4O | 410.521 | 4 / 0 | 3.1 | Yes |
43852 | CHEMBL170398 | C28H25N5O5 | 511.538 | 6 / 1 | 3.0 | No |
45343 | CHEMBL174592 | C34H28FN5O4 | 589.627 | 7 / 0 | 5.3 | No |
45692 | CHEMBL176797 | C25H22N4O | 394.478 | 3 / 1 | 4.6 | Yes |
48800 | CHEMBL540829 | C23H24ClN5O | 421.929 | 5 / 2 | N/A | N/A |
50764 | CHEMBL52369 | C31H38O8S2 | 602.757 | 9 / 0 | 5.8 | No |
52004 | CHEMBL3216197 | C26H28Cl2N4O | 483.437 | 4 / 2 | N/A | N/A |
53027 | CHEMBL427307 | C34H29N5O4 | 571.637 | 6 / 0 | 5.0 | No |
54180 | CHEMBL3215754 | C22H22Cl2N4O | 429.345 | 4 / 2 | N/A | N/A |
55773 | CHEMBL340544 | C26H25N3O | 395.506 | 3 / 0 | 4.1 | Yes |
57206 | CHEMBL173304 | C26H29N5O4 | 475.549 | 6 / 0 | 2.9 | Yes |
59840 | CHEMBL127010 | C31H53IN2O5 | 660.678 | 6 / 0 | N/A | No |
61412 | CHEMBL100190 | C25H29N5O2 | 431.54 | 5 / 0 | 1.4 | Yes |
61851 | CHEMBL103636 | C22H23F3N4O | 416.448 | 7 / 0 | 3.1 | Yes |
63931 | CHEMBL173531 | C26H30ClN5O2 | 480.009 | 5 / 0 | 3.5 | Yes |
64515 | CHEMBL125419 | C37H61NO7S2 | 696.015 | 8 / 0 | N/A | No |
66677 | CHEMBL127183 | C26H54NO6P | 507.693 | 6 / 0 | 7.5 | No |
66833 | CHEMBL322184 | C26H27N5O | 425.536 | 5 / 1 | 2.7 | Yes |
71191 | CHEMBL335853 | C25H24N4S | 412.555 | 4 / 0 | 3.8 | Yes |
71524 | CHEMBL176678 | C30H31FN6O2 | 526.616 | 6 / 0 | 4.2 | No |
71705 | CHEMBL131597 | C25H25N5O | 411.509 | 4 / 1 | 3.0 | Yes |
72244 | CHEMBL423711 | C28H26N4O | 434.543 | 4 / 0 | 4.1 | Yes |
73129 | CHEMBL300910 | C32H37NO9S2 | 643.766 | 11 / 0 | 4.1 | No |
74681 | CHEMBL3216401 | C27H30Cl2N4O | 497.464 | 4 / 2 | N/A | N/A |
75904 | CHEMBL368657 | C30H29N5O4 | 523.593 | 6 / 0 | 4.3 | No |
76382 | CHEMBL424947 | C26H22N4O4 | 454.486 | 6 / 1 | 4.0 | Yes |
78314 | CHEMBL338977 | C38H65NO6S2 | 696.059 | 7 / 0 | N/A | No |
79433 | CHEMBL133921 | C26H26N4O | 410.521 | 4 / 0 | 3.4 | Yes |
82261 | CHEMBL103753 | C26H26N4O2 | 426.52 | 5 / 1 | 2.2 | Yes |
82464 | CHEMBL124394 | C33H56IN3O6 | 717.73 | 8 / 1 | N/A | No |
84290 | CHEMBL427121 | C26H23N5O2 | 437.503 | 4 / 0 | 3.7 | Yes |
84398 | CHEMBL125315 | C38H65NO6S2 | 696.059 | 7 / 0 | N/A | No |
84965 | CHEMBL338940 | C26H26N4O2 | 426.52 | 5 / 1 | 2.2 | Yes |
85406 | CHEMBL124985 | C35H61IN2O5 | 716.786 | 6 / 0 | N/A | No |
87137 | CHEMBL127464 | C33H53NO7S2 | 639.907 | 8 / 0 | N/A | No |
88467 | CHEMBL52419 | C33H43NO8S2 | 645.826 | 10 / 0 | 5.9 | No |
90195 | CHEMBL103287 | C25H31N5O | 417.557 | 5 / 0 | 2.3 | Yes |
90689 | CHEMBL132655 | C27H26ClN3O | 443.975 | 3 / 0 | 5.0 | Yes |
92512 | CHEMBL338345 | C35H60IN3O6 | 745.784 | 8 / 1 | N/A | No |
92638 | CHEMBL172949 | C30H25N5O3 | 503.562 | 5 / 0 | 4.4 | No |
93748 | ABT-491 free base | C28H22FN5O2 | 479.515 | 5 / 0 | 4.0 | Yes |
97731 | CHEMBL174198 | C29H26N4O4 | 494.551 | 5 / 0 | 4.6 | Yes |
97816 | CHEMBL131690 | C25H27N3O | 385.511 | 3 / 0 | 3.3 | Yes |
97964 | CHEMBL125080 | C33H57IN2O5 | 688.732 | 6 / 0 | N/A | No |
99293 | CHEMBL134877 | C26H28N4O | 412.537 | 3 / 0 | 3.1 | Yes |
99564 | CHEMBL423717 | C25H26N4O2 | 414.509 | 4 / 1 | 2.4 | Yes |
100180 | CHEMBL124906 | C35H60IN3O6 | 745.784 | 8 / 1 | N/A | No |
100776 | CHEMBL172819 | C28H26N4O3 | 466.541 | 5 / 0 | 4.3 | Yes |
100920 | CHEMBL431049 | C29H31N5O3 | 497.599 | 6 / 1 | 3.0 | Yes |
103624 | CHEMBL554463 | C21H26ClN5O | 399.923 | 5 / 2 | N/A | N/A |
103827 | CHEMBL101342 | C27H28N6O3 | 484.56 | 7 / 2 | 2.2 | Yes |
104291 | CHEMBL338519 | C33H57IN2O4 | 672.733 | 5 / 0 | N/A | No |
105011 | CHEMBL127009 | C39H67NO6S2 | 710.086 | 7 / 0 | N/A | No |
105030 | CHEMBL367530 | C29H28N6O3 | 508.582 | 5 / 0 | 3.1 | No |
106475 | CHEMBL103231 | C27H29N5O3S | 503.621 | 7 / 1 | 2.5 | No |
106484 | CHEMBL170370 | C26H22BrN5O2 | 516.399 | 4 / 0 | 4.4 | No |
106593 | CHEMBL545773 | C27H30ClN5O | 476.021 | 5 / 2 | N/A | N/A |
107199 | CHEMBL367425 | C27H31N5O4 | 489.576 | 6 / 0 | 3.5 | Yes |
108487 | CHEMBL171294 | C27H30N6O4 | 502.575 | 7 / 0 | 2.5 | No |
108490 | CHEMBL173104 | C26H22FN5O2 | 455.493 | 5 / 0 | 4.0 | Yes |
110453 | CHEMBL336816 | C27H29N5O | 439.563 | 5 / 1 | 3.1 | Yes |
110468 | CHEMBL100547 | C27H29N5O | 439.563 | 5 / 1 | 4.0 | Yes |
111413 | CHEMBL3216628 | C25H29Cl2N3O | 458.427 | 3 / 3 | N/A | N/A |
112370 | CHEMBL103801 | C27H29N5O | 439.563 | 5 / 1 | 2.6 | Yes |
112741 | CHEMBL100853 | C21H25N5O | 363.465 | 5 / 1 | 0.9 | Yes |
119323 | CHEMBL552771 | C19H29ClN4O | 364.918 | 4 / 1 | N/A | N/A |
121251 | CHEMBL552805 | C28H32ClN5O | 490.048 | 5 / 2 | N/A | N/A |
121988 | CHEMBL126016 | C33H57IN2O5 | 688.732 | 6 / 0 | N/A | No |
122195 | CHEMBL124581 | C37H63NO6S2 | 682.032 | 7 / 0 | N/A | No |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417