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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL101342
Molecular formula	C27H28N6O3
IUPAC name	N-[3-[4-[cyano-(2-methylpyridin-3-yl)methyl]piperazin-1-yl]-3-oxo-1-phenylpropyl]-3-hydroxypyridine-2-carboxamide
Molecular weight	484.56
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	2.2
Synonyms	SCHEMBL9575112 BDBM50046011 N-[1-Phenyl-3-oxo-3-[4-[cyano(2-methyl-3-pyridyl)methyl]piperazin-1-yl]propyl]-3-hydroxypyridine-2-carboxamide 3-Hydroxy-pyridine-2-carboxylic acid (3-{4-[cyano-(2-methyl-pyridin-3-yl)-methyl]-piperazin-1-yl}-3-oxo-1-phenyl-propyl)-amide
Inchi Key	GRVWQHQUUBLDEM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28N6O3/c1-19-21(9-5-11-29-19)23(18-28)32-13-15-33(16-14-32)25(35)17-22(20-7-3-2-4-8-20)31-27(36)26-24(34)10-6-12-30-26/h2-12,22-23,34H,13-17H2,1H3,(H,31,36)
PubChem CID	11755085
ChEMBL	CHEMBL101342
IUPHAR	N/A
BindingDB	50046011
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
103825	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341
103826	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
103827	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341

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