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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

NamePlatelet-activating factor receptor
SpeciesCavia porcellus (Guinea pig)
GenePTAFR
SynonymPAF-R
PAFr
DiseaseN/A for non-human GPCRs
Length342
Amino acid sequenceMELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProtP21556
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5136
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 1371
Page:  / 14 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
2002D structureCHEMBL151310C23H37NO4391.5524 / 04.2Yes
9162D structureCHEMBL46754C37H56NO5PS657.8916 / 012.6No
16832D structureCHEMBL52933C27H26F2N2O432.5154 / 16.4No
16852D structureCHEMBL54935C27H26F2N2O432.5154 / 16.4No
5197092D structureCHEMBL351410C32H55N2O5+547.8015 / 08.8No
5197102D structureCHEMBL126981C33H57N2O5+561.8285 / 08.7No
5197112D structureCHEMBL157989C34H59N2O5+575.8555 / 09.9No
5197122D structureCHEMBL290840C34H59N2O5+575.8555 / 09.9No
5197132D structureCHEMBL160994C34H59N2O5+575.8555 / 09.9No
33702D structureCID 15005336C32H30ClN5O3568.0746 / 25.6No
41262D structureCHEMBL158974C33H57IN2O6704.7317 / 0N/ANo
42522D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-1,4-dihydro-5H-1-benzazepin-5-oneC23H18N4O366.4244 / 13.9Yes
5197162D structureCHEMBL12183C33H56N3O5S+606.8876 / 19.2No
43432D structureCHEMBL101957C28H30N4O438.5754 / 13.5Yes
46692D structureCHEMBL46870C32H44NO6PS601.7397 / 09.6No
5197182D structureBDBM50004624C31H27ClN4O4555.0317 / 15.0No
50792D structureCHEMBL99053C30H25FN4O2S524.6145 / 04.4No
54162D structureCHEMBL418989C28H31N5O3S517.6487 / 02.9No
57842D structureCHEMBL53014C30H26N2O3462.5494 / 16.2No
5197242D structureCHEMBL559013C21H21N5O359.4334 / 11.7Yes
61692D structureCHEMBL134025C16H22N4O286.3794 / 01.3Yes
69322D structureCHEMBL127766C36H61NO6S2668.0057 / 0N/ANo
75762D structureCHEMBL339676C36H59NO6S2665.9897 / 0N/ANo
79082D structureCHEMBL6263C36H53N3O10687.83110 / 05.7No
79292D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-chloro-3-pyridinyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl esterC33H28ClN7O3606.0838 / 24.8No
5197312D structureCHEMBL127875C30H56NO4S+526.8415 / 09.6No
5197322D structureCHEMBL127009C32H60NO3S+538.8964 / 010.9No
83702D structureCHEMBL417563C19H17N3O3S367.4236 / 12.6Yes
84452D structureCID 15005360C33H27ClN6O4607.0677 / 34.4No
4420602D structureGinkgolide CC20H24O11440.40111 / 4-1.4No
90892D structureCHEMBL347488C20H24O11440.40111 / 4-1.4No
4420612D structureCHEMBL3349895C20H24O11440.40111 / 4-1.4No
90922D structureCHEMBL156251C20H24O11440.40111 / 4-1.4No
93732D structureCHEMBL62322C26H32FNO2409.5454 / 15.1No
5197352D structureCHEMBL127416C28H50NO3S+480.7724 / 09.6No
100742D structureCHEMBL12352C35H60ClN3O6654.337 / 1N/ANo
108332D structureCHEMBL3216875C27H29Cl2N3O2498.4485 / 2N/AN/A
110942D structureCHEMBL291177C30H42NO5PS559.7026 / 09.9No
113712D structureCHEMBL1788193C34H60ClN3O6642.3197 / 1N/ANo
113722D structureCHEMBL2093039C34H60ClN3O6642.3197 / 1N/ANo
113742D structureCV-6209C34H60ClN3O6642.3197 / 1N/ANo
120482D structureLEXIPAFANTC23H30N4O4S458.5777 / 03.5Yes
122442D structureCID 15005338C33H29ClN4O3565.076 / 26.0No
127952D structureCHEMBL174262C25H20N4O3424.465 / 13.7Yes
137502D structureCHEMBL421843C32H55IN2O6690.7047 / 0N/ANo
140092D structureCHEMBL68407C25H30INO5551.4216 / 0N/ANo
5197492D structureBDBM50004615C33H33ClN4O4585.1017 / 05.8No
146532D structureCHEMBL125576C33H56ClN3O6626.2768 / 1N/ANo
148652D structureCHEMBL318908C27H27N5O2453.5466 / 04.0Yes
5197542D structureCHEMBL340480C31H55N2O4+519.7914 / 18.7No
150582D structureCHEMBL47192C28H38NO5PS531.6486 / 08.8No
152512D structureCHEMBL421954C27H36O5440.585 / 06.1No
157782D structureCHEMBL118182C21H16N6O368.45 / 12.2Yes
165262D structureCHEMBL64209C20H21N3O3S2415.5266 / 12.8Yes
5197652D structureCHEMBL349327C33H51N2O4+539.7814 / 09.2No
178222D structureCHEMBL300742C27H26F2N2O432.5154 / 16.4No
181412D structureCHEMBL103571C28H29N5O2467.5735 / 03.1Yes
5197752D structureCHEMBL554536C17H14ClN3OS343.8294 / 13.1Yes
5197832D structureBDBM50004634C35H29N7O3595.6638 / 14.1No
201612D structureCHEMBL443811C27H44N4O440.6764 / 07.3No
5197872D structureCHEMBL338883C28H50NO4S+496.7715 / 09.4No
210702D structureCHEMBL48129C32H46NO5PS587.7566 / 011.0No
219932D structureCHEMBL367418C30H30FN5O2511.6015 / 04.8No
220202D structureCHEMBL132028C26H34N2O8502.5648 / 02.4No
222242D structureCHEMBL66814C24H34INO5543.4426 / 0N/ANo
5197992D structureBDBM50014011C16H25NO4S327.4396 / 02.5Yes
229452D structureCHEMBL47159C33H46NO6PS615.7667 / 010.0No
5198052D structureCHEMBL545773C27H29N5O439.5635 / 13.0Yes
5198112D structureCHEMBL124312C30H62NO3+484.833 / 010.1No
5198122D structureCHEMBL64493C24H21N3O2S415.5115 / 14.0Yes
5198152D structureCHEMBL154459C34H53N2O3+537.8093 / 010.0No
256482D structureCHEMBL118672C27H27N7O2481.566 / 02.6Yes
258402D structureCHEMBL3215984C18H20Cl2N4O379.2854 / 2N/AN/A
5198162D structureBDBM50006101C30H54N2O6PS-601.8047 / 18.0No
262122D structureCHEMBL1160088C30H55N2O6PS602.8127 / 28.0No
264582D structureCHEMBL268597C32H42N2O10614.69210 / 04.2No
267322D structureCHEMBL103903C27H26N4O422.5324 / 04.3Yes
271592D structureCHEMBL545072C27H30ClN5O476.0215 / 1N/AN/A
278802D structureCHEMBL338689C32H55IN2O5674.7056 / 0N/ANo
279462D structureCHEMBL273638C42H65ClN4O6757.4547 / 1N/ANo
5581192D structureCHEMBL325928C21H19N7O385.4315 / 12.0Yes
289792D structureCHEMBL20522C29H62BrNO4568.7225 / 1N/ANo
5198292D structureCHEMBL64860C25H21N3O3S443.5216 / 14.1Yes
5198332D structureCHEMBL421618C31H53N2O4+517.7754 / 09.0No
297142D structureCHEMBL118793C24H25N7O427.5125 / 02.9Yes
308512D structureCHEMBL65715C28H37FN2O4484.6126 / 43.8Yes
313072D structureCHEMBL64860C27H23N3O7S533.55510 / 3N/ANo
314992D structureCHEMBL295148C34H50NO5PS615.816 / 011.4No
315752D structureCHEMBL24879C34H49N3O10659.77710 / 15.3No
5198462D structureCHEMBL66185C26H46NO5+452.6565 / 07.0No
317952D structureCHEMBL103561C28H31N5O453.595 / 13.3Yes
5198502D structureCHEMBL12554C35H60N3O6+618.886 / 19.5No
5198512D structureCHEMBL12882C35H60N3O6+618.886 / 19.5No
5198522D structureCHEMBL340164C31H58NO3S+524.8694 / 010.2No
325222D structureCHEMBL64636C23H18FN3O2S419.4746 / 24.0Yes
331192D structureCHEMBL2114378C22H24O6384.4286 / 03.2Yes
331202D structureCHEMBL2115333C22H24O6384.4286 / 03.2Yes
331622D structureCHEMBL127531C24H50NO5P463.645 / 06.7No
335852D structureCHEMBL293653C19H19N3O3S369.4396 / 22.3Yes
336612D structureCHEMBL102070C27H28N6O2468.5616 / 11.7Yes

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