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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL134025
Molecular formula	C16H22N4O
IUPAC name	2-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]-2-pyridin-3-ylacetonitrile
Molecular weight	286.379
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	1.3
Synonyms	2-[4-(2,2-Dimethylpropionyl)-1-piperazinyl]-2-(3-pyridinyl)acetonitrile [4-(2,2-Dimethyl-propionyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile BDBM50003500 SCHEMBL9852903
Inchi Key	AIFRPOVILWOZEW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H22N4O/c1-16(2,3)15(21)20-9-7-19(8-10-20)14(11-17)13-5-4-6-18-12-13/h4-6,12,14H,7-10H2,1-3H3
PubChem CID	10085405
ChEMBL	CHEMBL134025
IUPHAR	N/A
BindingDB	50003500
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6168	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
6169	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342

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