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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Cavia porcellus (Guinea pig)
Gene	PTAFR
Synonym	PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	342
Amino acid sequence	MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProt	P21556
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5136
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CID 15005360
Molecular formula	C33H27ClN6O4
IUPAC name	ethyl 4-(2-chlorophenyl)-6-methyl-2-[4-(2-oxo-3H-imidazo[4,5-c]pyridin-1-yl)phenyl]-5-(pyridin-2-ylcarbamoyl)-1,4-dihydropyridine-3-carboxylate
Molecular weight	607.067
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	4.4
Synonyms	N/A
Inchi Key	ALODDZNMHPILEN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H27ClN6O4/c1-3-44-32(42)29-28(22-8-4-5-9-23(22)34)27(31(41)39-26-10-6-7-16-36-26)19(2)37-30(29)20-11-13-21(14-12-20)40-25-15-17-35-18-24(25)38-33(40)43/h4-18,28,37H,3H2,1-2H3,(H,38,43)(H,36,39,41)
PubChem CID	15005360
ChEMBL	CHEMBL107198
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1400.0 nM	PMID1507200	ChEMBL

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