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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Cavia porcellus (Guinea pig)
Gene	PTAFR
Synonym	PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	342
Amino acid sequence	MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProt	P21556
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5136
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL127875
Molecular formula	C30H56NO4S+
IUPAC name	3-[6-[[2-(hexadecoxymethyl)-1,3-dioxolan-4-yl]methoxy]hexyl]-1,3-thiazol-3-ium
Molecular weight	526.841
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	9.6
Synonyms	BDBM50011077 Toluene-4-sulfonate3-[6-(2-hexadecyloxymethyl-[1,3]dioxolan-4-ylmethoxy)-hexyl]-thiazol-3-ium;Toluene-4-sulfonate 3-[6-(2-Hexadecyloxymethyl-1,3-dioxolan-4-ylmethoxy)hexyl]thiazolium CHEMBL1180490
Inchi Key	ALEBAPAAKCIABV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H56NO4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-23-33-27-30-34-26-29(35-30)25-32-22-19-16-14-17-20-31-21-24-36-28-31/h21,24,28-30H,2-20,22-23,25-27H2,1H3/q+1
PubChem CID	14785926
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50011077
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1300.0 nM	PMID1992139	BindingDB

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