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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-chloro-3-pyridinyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester
Molecular formula	C33H28ClN7O3
IUPAC name	ethyl 4-(2-chloropyridin-3-yl)-6-methyl-2-[4-(2-methylimidazo[4,5-c]pyridin-1-yl)phenyl]-5-(pyridin-2-ylcarbamoyl)-1,4-dihydropyridine-3-carboxylate
Molecular weight	606.083
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.8
Synonyms	N/A
Inchi Key	AKVDDBVLYGVUJX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H28ClN7O3/c1-4-44-33(43)29-28(23-8-7-16-37-31(23)34)27(32(42)40-26-9-5-6-15-36-26)19(2)38-30(29)21-10-12-22(13-11-21)41-20(3)39-24-18-35-17-14-25(24)41/h5-18,28,38H,4H2,1-3H3,(H,36,40,42)
PubChem CID	15005378
ChEMBL	CHEMBL106800
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7928	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341
7929	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342

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