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| Name | Platelet-activating factor receptor |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Ptafr |
| Synonym | AGEPC receptor PAF receptor PAF-R PAFr |
| Disease | N/A for non-human GPCRs |
| Length | 341 |
| Amino acid sequence | MEHNGSFRVDSEFRYTLFPIVYSVIFILGVVANGYVLWVFANLYPSKKLNEIKIFMVNLTMADLLFLITLPLWIVYYYNEGDWILPNFLCNVAGCLFFINTYCSVAFLGVITYNRYQAVAYPIKTAQATTRKRGISLSLIIWVSIVATASYFLATDSTNLVPNKDGSGNITRCFEHYEPYSVPILVVHVFIAFCFFLVFFLIFYCNLVIIHTLLTQPMRQQRKAGVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFRKHLSEKFYSMRSSRKCSRATSDTCTEVIVPANQTPIVSLKN |
| UniProt | Q62035 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3993 |
| IUPHAR | 334 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3371 |  CID 15005336 | C32H30ClN5O3 | 568.074 | 6 / 2 | 5.6 | No |
| 4251 |  2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-1,4-dihydro-5H-1-benzazepin-5-one | C23H18N4O | 366.424 | 4 / 1 | 3.9 | Yes |
| 4342 |  CHEMBL101957 | C28H30N4O | 438.575 | 4 / 1 | 3.5 | Yes |
| 5415 |  CHEMBL418989 | C28H31N5O3S | 517.648 | 7 / 0 | 2.9 | No |
| 7928 |  2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-chloro-3-pyridinyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester | C33H28ClN7O3 | 606.083 | 8 / 2 | 4.8 | No |
| 553292 |  7-epi-ginkgolide C | C20H24O11 | 440.401 | 11 / 4 | -1.4 | No |
| 553293 |  Ginkgolide C | C20H24O11 | 440.401 | 11 / 4 | -1.4 | No |
| 12243 |  CID 15005338 | C33H29ClN4O3 | 565.07 | 6 / 2 | 6.0 | No |
| 14864 |  CHEMBL318908 | C27H27N5O2 | 453.546 | 6 / 0 | 4.0 | Yes |
| 18139 |  CHEMBL103571 | C28H29N5O2 | 467.573 | 5 / 0 | 3.1 | Yes |
| 26733 |  CHEMBL103903 | C27H26N4O | 422.532 | 4 / 0 | 4.3 | Yes |
| 27158 |  CHEMBL545072 | C27H30ClN5O | 476.021 | 5 / 1 | N/A | N/A |
| 31797 |  CHEMBL103561 | C28H31N5O | 453.59 | 5 / 1 | 3.3 | Yes |
| 33660 |  CHEMBL102070 | C27H28N6O2 | 468.561 | 6 / 1 | 1.7 | Yes |
| 34963 |  CHEMBL102918 | C28H29N5O2 | 467.573 | 5 / 1 | 2.8 | Yes |
| 36381 |  CHEMBL1203313 | C22H28ClN5O | 413.95 | 5 / 2 | N/A | N/A |
| 37974 |  CHEMBL542731 | C26H29ClN4 | 432.996 | 4 / 1 | N/A | N/A |
| 40243 |  CHEMBL318163 | C24H27N5O3 | 433.512 | 6 / 0 | 1.5 | Yes |
| 40933 |  CHEMBL320900 | C33H28ClN5O3S | 610.129 | 7 / 2 | 7.1 | No |
| 41304 |  CHEMBL555567 | C26H30ClN5 | 448.011 | 5 / 2 | N/A | N/A |
| 49111 |  CHEMBL133120 | C25H25N3O3 | 415.493 | 3 / 0 | 1.9 | Yes |
| 50217 |  CHEMBL154459 | C34H53IN2O3 | 664.713 | 4 / 0 | N/A | No |
| 52005 |  CHEMBL3216197 | C26H28Cl2N4O | 483.437 | 4 / 2 | N/A | N/A |
| 55774 |  CHEMBL340544 | C26H25N3O | 395.506 | 3 / 0 | 4.1 | Yes |
| 57621 |  CHEMBL422160 | C31H47IN2O4 | 638.631 | 5 / 0 | N/A | No |
| 61071 |  CHEMBL103694 | C29H34N4O2 | 470.617 | 5 / 0 | 4.2 | Yes |
| 61411 |  CHEMBL100190 | C25H29N5O2 | 431.54 | 5 / 0 | 1.4 | Yes |
| 61850 |  CHEMBL103636 | C22H23F3N4O | 416.448 | 7 / 0 | 3.1 | Yes |
| 64606 |  CHEMBL350961 | C39H40ClN7O3S | 722.305 | 10 / 0 | 6.8 | No |
| 66831 |  CHEMBL322184 | C26H27N5O | 425.536 | 5 / 1 | 2.7 | Yes |
| 70577 |  2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(3-pyridinyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester | C33H29N7O3 | 571.641 | 8 / 2 | 3.9 | No |
| 71192 |  CHEMBL335853 | C25H24N4S | 412.555 | 4 / 0 | 3.8 | Yes |
| 71706 |  CHEMBL131597 | C25H25N5O | 411.509 | 4 / 1 | 3.0 | Yes |
| 72242 |  CHEMBL423711 | C28H26N4O | 434.543 | 4 / 0 | 4.1 | Yes |
| 74017 |  CHEMBL408135 | C39H38ClN7O4S | 736.288 | 10 / 0 | 6.4 | No |
| 74683 |  CHEMBL3216401 | C27H30Cl2N4O | 497.464 | 4 / 2 | N/A | N/A |
| 74914 |  CID 15005335 | C31H28ClN5O3 | 554.047 | 6 / 2 | 5.2 | No |
| 78403 |  2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-chlorophenyl)-5-carbamoyl-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester | C29H26ClN5O3 | 528.009 | 6 / 2 | 4.3 | No |
| 79434 |  CHEMBL133921 | C26H26N4O | 410.521 | 4 / 0 | 3.4 | Yes |
| 82260 |  CHEMBL103753 | C26H26N4O2 | 426.52 | 5 / 1 | 2.2 | Yes |
| 84260 |  CHEMBL164665 | C37H36ClN7O3S | 694.251 | 10 / 1 | 3.8 | No |
| 553692 |  Ginkgolide A | C20H24O9 | 408.403 | 9 / 2 | 0.6 | Yes |
| 84966 |  CHEMBL338940 | C26H26N4O2 | 426.52 | 5 / 1 | 2.2 | Yes |
| 86453 |  CHEMBL347593 | C30H47IN2O2 | 594.622 | 3 / 0 | N/A | No |
| 86908 |  CHEMBL320676 | C24H27N5O | 401.514 | 5 / 1 | 1.5 | Yes |
| 89038 |  CHEMBL119847 | C23H19N5O | 381.439 | 4 / 0 | 3.1 | Yes |
| 90688 |  CHEMBL132655 | C27H26ClN3O | 443.975 | 3 / 0 | 5.0 | Yes |
| 93237 |  CHEMBL349150 | C40H41ClN6O2S | 705.318 | 8 / 0 | 7.9 | No |
| 97817 |  CHEMBL131690 | C25H27N3O | 385.511 | 3 / 0 | 3.3 | Yes |
| 100919 |  CHEMBL431049 | C29H31N5O3 | 497.599 | 6 / 1 | 3.0 | Yes |
| 103626 |  CHEMBL554463 | C21H26ClN5O | 399.923 | 5 / 2 | N/A | N/A |
| 103825 |  CHEMBL101342 | C27H28N6O3 | 484.56 | 7 / 2 | 2.2 | Yes |
| 104419 |  CHEMBL323798 | C39H38ClN7O4S | 736.288 | 10 / 0 | 6.4 | No |
| 106474 |  CHEMBL103231 | C27H29N5O3S | 503.621 | 7 / 1 | 2.5 | No |
| 106592 |  CHEMBL545773 | C27H30ClN5O | 476.021 | 5 / 2 | N/A | N/A |
| 553786 |  7alpha-Cl-ginkgolide B | C20H23ClO10 | 458.844 | 10 / 3 | -0.1 | Yes |
| 110452 |  CHEMBL336816 | C27H29N5O | 439.563 | 5 / 1 | 3.1 | Yes |
| 110469 |  CHEMBL100547 | C27H29N5O | 439.563 | 5 / 1 | 4.0 | Yes |
| 110799 |  CHEMBL157123 | C31H47IN2O4 | 638.631 | 5 / 0 | N/A | No |
| 112142 |  CHEMBL349582 | C31H47IN2O4 | 638.631 | 5 / 0 | N/A | No |
| 112371 |  CHEMBL103801 | C27H29N5O | 439.563 | 5 / 1 | 2.6 | Yes |
| 112740 |  CHEMBL100853 | C21H25N5O | 363.465 | 5 / 1 | 0.9 | Yes |
| 113723 |  CHEMBL335974 | C34H32O12 | 632.618 | 12 / 2 | 3.2 | No |
| 119322 |  CHEMBL552771 | C19H29ClN4O | 364.918 | 4 / 1 | N/A | N/A |
| 121252 |  CHEMBL552805 | C28H32ClN5O | 490.048 | 5 / 2 | N/A | N/A |
| 121401 |  CHEMBL164123 | C39H40ClN7O3S | 722.305 | 10 / 0 | 6.8 | No |
| 122301 |  CHEMBL421204 | C22H26N6O2 | 406.49 | 5 / 2 | 0.6 | Yes |
| 122462 |  CHEMBL541330 | C20H24ClN3O5 | 421.878 | 6 / 1 | N/A | N/A |
| 123457 |  CHEMBL116198 | C22H15Cl2N5O | 436.296 | 4 / 1 | 4.2 | Yes |
| 127239 |  CHEMBL3215980 | C20H24Cl2N4O | 407.339 | 4 / 2 | N/A | N/A |
| 131150 |  CID 15005355 | C32H29ClN4O3S | 585.119 | 7 / 2 | 6.5 | No |
| 553948 |  7alpha-NHMe-ginkgolide B | C21H27NO10 | 453.444 | 11 / 4 | -1.1 | No |
| 132450 |  CHEMBL100522 | C26H27N5O2 | 441.535 | 6 / 1 | 1.5 | Yes |
| 138803 |  CHEMBL340989 | C27H27N5O2 | 453.546 | 5 / 1 | 2.6 | Yes |
| 142237 |  CHEMBL337840 | C34H34O12 | 634.634 | 12 / 3 | 2.0 | No |
| 554001 |  7alpha-OCOCH2Ph-ginkgolide B | C28H30O12 | 558.536 | 12 / 3 | 0.8 | No |
| 145086 |  CHEMBL351224 | C45H45ClN8O3S | 813.418 | 11 / 0 | 7.7 | No |
| 146447 |  2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-pyridinyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester | C33H29N7O3 | 571.641 | 8 / 2 | 3.9 | No |
| 150075 |  CHEMBL100497 | C28H31N5O | 453.59 | 5 / 1 | 2.9 | Yes |
| 150495 |  Apafant | C22H22ClN5O2S | 455.961 | 6 / 0 | 1.1 | Yes |
| 151978 |  2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(1,3-benzodioxol-4-yl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester | C35H30N6O5 | 614.662 | 9 / 2 | 4.7 | No |
| 152134 |  CHEMBL335310 | C29H29F3N2O11 | 638.549 | 16 / 3 | 1.7 | No |
| 154292 |  CHEMBL339997 | C27H25F4N3O10 | 627.502 | 16 / 2 | 3.0 | No |
| 155871 |  CHEMBL335044 | C26H26N4O | 410.521 | 4 / 0 | 3.5 | Yes |
| 156350 |  CHEMBL346722 | C44H73IN2O4 | 820.982 | 5 / 0 | N/A | No |
| 158793 |  CHEMBL134143 | C27H25N3O | 407.517 | 3 / 0 | 3.8 | Yes |
| 159317 |  CHEMBL100281 | C27H28N6O3 | 484.56 | 6 / 2 | 1.8 | Yes |
| 162881 |  2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(4-cyanophenyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester | C35H29N7O3 | 595.663 | 8 / 2 | 4.7 | No |
| 164959 |  CHEMBL103465 | C27H31N3O2 | 429.564 | 4 / 1 | 3.1 | Yes |
| 165915 |  CHEMBL100340 | C24H29N5O3 | 435.528 | 6 / 0 | 1.7 | Yes |
| 166422 |  CHEMBL154856 | C30H45F3N2O5S | 602.754 | 8 / 1 | N/A | No |
| 170020 |  CHEMBL155003 | C31H47IN2O4 | 638.631 | 5 / 1 | N/A | No |
| 173537 |  CHEMBL99833 | C22H26N4O2 | 378.476 | 5 / 1 | 1.3 | Yes |
| 173595 |  CHEMBL130606 | C34H34O11 | 618.635 | 11 / 2 | 3.0 | No |
| 175360 |  CHEMBL133457 | C27H29N5O | 439.563 | 5 / 1 | 2.6 | Yes |
| 175884 |  CHEMBL103761 | C35H37N5O | 543.715 | 5 / 0 | 4.8 | No |
| 176881 |  CID 15005334 | C33H32ClN5O3 | 582.101 | 6 / 2 | 6.0 | No |
| 177218 |  CHEMBL103619 | C25H27N5O3 | 445.523 | 6 / 0 | 0.7 | Yes |
| 179931 |  CHEMBL423891 | C20H20N4O | 332.407 | 4 / 0 | 2.0 | Yes |
| 185723 |  CHEMBL154205 | C30H45IN2O3 | 608.605 | 4 / 0 | N/A | No |
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