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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL131690
Molecular formula	C25H27N3O
IUPAC name	3,3-diphenyl-1-[4-(pyridin-3-ylmethyl)piperazin-1-yl]propan-1-one
Molecular weight	385.511
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.3
Synonyms	1-[4-(3-Pyridinylmethyl)-1-piperazinyl]-3,3-diphenyl-1-propanone AKOS028884920 3,3-Diphenyl-1-(4-pyridin-3-ylmethyl-piperazin-1-yl)-propan-1-one; hydrate BDBM50003488
Inchi Key	GJDOBZATTIEGBR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H27N3O/c29-25(28-16-14-27(15-17-28)20-21-8-7-13-26-19-21)18-24(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-13,19,24H,14-18,20H2
PubChem CID	10045642
ChEMBL	CHEMBL131690
IUPHAR	N/A
BindingDB	50003488
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
97815	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
97816	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
97817	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341

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