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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL133921
Molecular formula	C26H26N4O
IUPAC name	2-[4-(2,2-diphenylacetyl)piperazin-1-yl]-2-pyridin-3-ylpropanenitrile
Molecular weight	410.521
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.4
Synonyms	BDBM50003551 SCHEMBL9852934 2-(4-Diphenylacetyl-piperazin-1-yl)-2-pyridin-3-yl-propionitrile; hydrate 2-(3-Pyridinyl)-2-[4-(1-oxo-2,2-diphenylethyl)-1-piperazinyl]propanenitrile
Inchi Key	FIVIVGVDQOVQOF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26N4O/c1-26(20-27,23-13-8-14-28-19-23)30-17-15-29(16-18-30)25(31)24(21-9-4-2-5-10-21)22-11-6-3-7-12-22/h2-14,19,24H,15-18H2,1H3
PubChem CID	10092996
ChEMBL	CHEMBL133921
IUPHAR	N/A
BindingDB	50003551
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
79433	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
79434	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341
79435	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342

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