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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL103753
Molecular formula	C26H26N4O2
IUPAC name	2-[4-(3-hydroxy-3,3-diphenylpropanoyl)piperazin-1-yl]-2-pyridin-3-ylacetonitrile
Molecular weight	426.52
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.2
Synonyms	SCHEMBL9852905 [4-(3-Hydroxy-3,3-diphenyl-propionyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile [4-(3-Hydroxy-3,3-diphenyl-propionyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile; hydrate BDBM50003510
Inchi Key	FMTWOXJEAYZPIZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26N4O2/c27-19-24(21-8-7-13-28-20-21)29-14-16-30(17-15-29)25(31)18-26(32,22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-13,20,24,32H,14-18H2
PubChem CID	10410208
ChEMBL	CHEMBL103753
IUPHAR	N/A
BindingDB	50003510
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
82260	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341
82261	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
82262	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342

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