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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL320676
Molecular formula	C24H27N5O
IUPAC name	2-(2-methylpyridin-3-yl)-2-[4-[3-phenyl-3-(prop-2-ynylamino)propanoyl]piperazin-1-yl]acetonitrile
Molecular weight	401.514
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.5
Synonyms	BDBM50045957 SCHEMBL9575029 (2-Methyl-pyridin-3-yl)-[4-(3-phenyl-3-prop-2-ynylamino-propionyl)-piperazin-1-yl]-acetonitrile [4-[3-Phenyl-1-oxo-3-[(2-propynyl)amino]propyl]piperazin-1-yl](2-methyl-3-pyridyl)acetonitrile
Inchi Key	FTNUHMUEBLWYBC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27N5O/c1-3-11-27-22(20-8-5-4-6-9-20)17-24(30)29-15-13-28(14-16-29)23(18-25)21-10-7-12-26-19(21)2/h1,4-10,12,22-23,27H,11,13-17H2,2H3
PubChem CID	10318877
ChEMBL	CHEMBL320676
IUPHAR	N/A
BindingDB	50045957
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
86907	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
86908	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341

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