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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL421204
Molecular formula	C22H26N6O2
IUPAC name	[3-[4-[cyano-(2-methylpyridin-3-yl)methyl]piperazin-1-yl]-3-oxo-1-phenylpropyl]urea
Molecular weight	406.49
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	0.6
Synonyms	BDBM50046004 SCHEMBL9575045 (3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piperazin-1-yl}-3-oxo-1-phenyl-propyl)-urea [4-[3-Phenyl-1-oxo-3-ureidopropyl]piperazin-1-yl](2-methyl-3-pyridyl)acetonitrile
Inchi Key	HRPYXBODLSBBFG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26N6O2/c1-16-18(8-5-9-25-16)20(15-23)27-10-12-28(13-11-27)21(29)14-19(26-22(24)30)17-6-3-2-4-7-17/h2-9,19-20H,10-14H2,1H3,(H3,24,26,30)
PubChem CID	10341289
ChEMBL	CHEMBL421204
IUPHAR	N/A
BindingDB	50046004
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
122300	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
122301	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341

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