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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL338940
Molecular formula	C26H26N4O2
IUPAC name	2-[4-(3-hydroxy-3,3-diphenylpropanoyl)piperazin-1-yl]-2-pyridin-4-ylacetonitrile
Molecular weight	426.52
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.2
Synonyms	[4-(3-Hydroxy-3,3-diphenyl-propionyl)-piperazin-1-yl]-pyridin-4-yl-acetonitrile; hydrate BDBM50003499 SCHEMBL9852997
Inchi Key	FQQHZKLGYQTVQN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26N4O2/c27-20-24(21-11-13-28-14-12-21)29-15-17-30(18-16-29)25(31)19-26(32,22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14,24,32H,15-19H2
PubChem CID	10455159
ChEMBL	CHEMBL338940
IUPHAR	N/A
BindingDB	50003499
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
84964	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
84965	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
84966	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341

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