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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL423711
Molecular formula	C28H26N4O
IUPAC name	3-[cyano-[4-(3,3-diphenylpropanoyl)piperazin-1-yl]methyl]benzonitrile
Molecular weight	434.543
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.1
Synonyms	2-[4-(3,3-Diphenylpropionyl)-1-piperazinyl]-2-(3-cyanophenyl)acetonitrile BDBM50003498 3-{Cyano-[4-(3,3-diphenyl-propionyl)-piperazin-1-yl]-methyl}-benzonitrile
Inchi Key	DYSMKZWCHPKQDB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H26N4O/c29-20-22-8-7-13-25(18-22)27(21-30)31-14-16-32(17-15-31)28(33)19-26(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-13,18,26-27H,14-17,19H2
PubChem CID	9980372
ChEMBL	CHEMBL423711
IUPHAR	N/A
BindingDB	50003498
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72242	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341
72243	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
72244	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341

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