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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL103619
Molecular formula	C25H27N5O3
IUPAC name	2-[4-[3-(2,5-dioxopyrrolidin-1-yl)-3-phenylpropanoyl]piperazin-1-yl]-2-(2-methylpyridin-3-yl)acetonitrile
Molecular weight	445.523
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	0.7
Synonyms	SCHEMBL9575310 [4-[3-Phenyl-1-oxo-3-(2,5-dioxopyrrolidin-1-yl)propyl]piperazin-1-yl](2-methyl-3-pyridyl)acetonitrile
Inchi Key	KSOJRNIWBLEKEZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H27N5O3/c1-18-20(8-5-11-27-18)22(17-26)28-12-14-29(15-13-28)25(33)16-21(19-6-3-2-4-7-19)30-23(31)9-10-24(30)32/h2-8,11,21-22H,9-10,12-16H2,1H3
PubChem CID	10252942
ChEMBL	CHEMBL103619
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
177217	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
177218	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341

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