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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL133457
Molecular formula	C27H29N5O
IUPAC name	2-[4-[3-(benzhydrylamino)propanoyl]piperazin-1-yl]-2-pyridin-4-ylacetonitrile
Molecular weight	439.563
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.6
Synonyms	SCHEMBL9852953 {4-[3-(Benzhydryl-amino)-propionyl]-piperazin-1-yl}-pyridin-4-yl-acetonitrile; hydrate; diethylether BDBM50003556
Inchi Key	KQBOPEOVYVGIOG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H29N5O/c28-21-25(22-11-14-29-15-12-22)31-17-19-32(20-18-31)26(33)13-16-30-27(23-7-3-1-4-8-23)24-9-5-2-6-10-24/h1-12,14-15,25,27,30H,13,16-20H2
PubChem CID	10026204
ChEMBL	CHEMBL133457
IUPHAR	N/A
BindingDB	50003556
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
175358	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
175359	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
175360	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341

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