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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL100281
Molecular formula	C27H28N6O3
IUPAC name	N-[3-[4-[cyano-(2-methylpyridin-3-yl)methyl]piperazin-1-yl]-3-oxo-1-phenylpropyl]-2-oxo-1H-pyridine-3-carboxamide
Molecular weight	484.56
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	1.8
Synonyms	N-[1-Phenyl-3-oxo-3-[4-[cyano(2-methyl-3-pyridyl)methyl]piperazin-1-yl]propyl]-2-hydroxypyridine-3-carboxamide SCHEMBL9575100 BDBM50046008 N-(3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piperazin-1-yl}-3-oxo-1-phenyl-propyl)-2-hydroxy-nicotinamide
Inchi Key	JTDXUFVQNLHQCS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28N6O3/c1-19-21(9-5-11-29-19)24(18-28)32-13-15-33(16-14-32)25(34)17-23(20-7-3-2-4-8-20)31-27(36)22-10-6-12-30-26(22)35/h2-12,23-24H,13-17H2,1H3,(H,30,35)(H,31,36)
PubChem CID	10458039
ChEMBL	CHEMBL100281
IUPHAR	N/A
BindingDB	50046008
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
159315	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
159316	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
159317	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341

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