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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL335044
Molecular formula	C26H26N4O
IUPAC name	2-[4-(2,3-diphenylpropanoyl)piperazin-1-yl]-2-pyridin-3-ylacetonitrile
Molecular weight	410.521
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.5
Synonyms	BDBM50003516 SCHEMBL9853049 2-[4-(2,3-Diphenylpropionyl)-1-piperazinyl]-2-(3-pyridinyl)acetonitrile [4-(2,3-Diphenyl-propionyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile; hydrate
Inchi Key	JOGXXWAQGKTITB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26N4O/c27-19-25(23-12-7-13-28-20-23)29-14-16-30(17-15-29)26(31)24(22-10-5-2-6-11-22)18-21-8-3-1-4-9-21/h1-13,20,24-25H,14-18H2
PubChem CID	10476687
ChEMBL	CHEMBL335044
IUPHAR	N/A
BindingDB	50003516
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
155871	Platelet-activating factor receptor	Q62035	Ptafr	Mus musculus (Mouse)	341
155872	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342
155873	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341

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