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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Cavia porcellus (Guinea pig)
Gene	PTAFR
Synonym	PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	342
Amino acid sequence	MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProt	P21556
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5136
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL340480
Molecular formula	C31H55N2O4+
IUPAC name	[4-(hexadecoxymethyl)oxolan-2-yl]methyl N-[(1-ethylpyridin-1-ium-2-yl)methyl]carbamate
Molecular weight	519.791
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	8.7
Synonyms	1-Ethyl-2-[(4-hexadecyloxymethyl-tetrahydro-furan-2-ylmethoxycarbonylamino)-methyl]-pyridinium; iodide BDBM50011092 2-[[N-[[(Tetrahydro-4-hexadecyloxymethylfuran)-2-yl]methoxycarbonyl]amino]methyl]-1-ethylpyridinium CHEMBL1184239
Inchi Key	AURHGHMHMUQEIH-UHFFFAOYSA-O
Inchi ID	InChI=1S/C31H54N2O4/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-19-22-35-25-28-23-30(36-26-28)27-37-31(34)32-24-29-20-17-18-21-33(29)4-2/h17-18,20-21,28,30H,3-16,19,22-27H2,1-2H3/p+1
PubChem CID	14786005
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50011092
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	5300.0 nM	PMID1992139	BindingDB

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