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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Rattus norvegicus (Rat)
Gene	Ptafr
Synonym	AGEPC receptor PAF receptor PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MEQNGSFRVDSEFRYTLFPIVYSVIFVLGVVANGYVLWVFATLYPSKKLNEIKIFMVNLTVADLLFLMTLPLWIVYYSNEGDWIVHKFLCNLAGCLFFINTYCSVAFLGVITYNRYQAVAYPIKTAQATTRKRGITLSLVIWISIAATASYFLATDSTNVVPKKDGSGNITRCFEHYEPYSVPILVVHIFITSCFFLVFFLIFYCNMVIIHTLLTRPVRQQRKPEVKRRALWMVCTVLAVFVICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFRKHLSEKFYSMRSSRKCSRATSDTCTEVMMPANQTPVLPLKN
UniProt	P46002
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4127
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL132655
Molecular formula	C27H26ClN3O
IUPAC name	2-(3-chlorophenyl)-2-[4-(3,3-diphenylpropanoyl)piperazin-1-yl]acetonitrile
Molecular weight	443.975
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.0
Synonyms	(3-Chloro-phenyl)-[4-(3,3-diphenyl-propionyl)-piperazin-1-yl]-acetonitrile BDBM50003547 2-[4-(3,3-Diphenylpropionyl)-1-piperazinyl]-2-(3-chlorophenyl)acetonitrile
Inchi Key	FYZXXCWVPPJHHN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H26ClN3O/c28-24-13-7-12-23(18-24)26(20-29)30-14-16-31(17-15-30)27(32)19-25(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18,25-26H,14-17,19H2
PubChem CID	10026451
ChEMBL	CHEMBL132655
IUPHAR	N/A
BindingDB	50003547
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ID50	<5.0 mg.kg-1	PMID1433215	ChEMBL

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