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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Rattus norvegicus (Rat)
Gene	Ptafr
Synonym	AGEPC receptor PAF receptor PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MEQNGSFRVDSEFRYTLFPIVYSVIFVLGVVANGYVLWVFATLYPSKKLNEIKIFMVNLTVADLLFLMTLPLWIVYYSNEGDWIVHKFLCNLAGCLFFINTYCSVAFLGVITYNRYQAVAYPIKTAQATTRKRGITLSLVIWISIAATASYFLATDSTNVVPKKDGSGNITRCFEHYEPYSVPILVVHIFITSCFFLVFFLIFYCNMVIIHTLLTRPVRQQRKPEVKRRALWMVCTVLAVFVICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFRKHLSEKFYSMRSSRKCSRATSDTCTEVMMPANQTPVLPLKN
UniProt	P46002
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4127
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL418989
Molecular formula	C28H31N5O3S
IUPAC name	N-benzhydryl-N-[2-[4-[cyano-(2-methylpyridin-3-yl)methyl]piperazin-1-yl]-2-oxoethyl]methanesulfonamide
Molecular weight	517.648
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	2.9
Synonyms	N-Benzhydryl-N-(2-{4-[cyano-(2-methyl-pyridin-3-yl)-methyl]-piperazin-1-yl}-2-oxo-ethyl)-methanesulfonamide SCHEMBL9574988 BDBM50046016
Inchi Key	AHBUCMUWRMBHAS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H31N5O3S/c1-22-25(14-9-15-30-22)26(20-29)31-16-18-32(19-17-31)27(34)21-33(37(2,35)36)28(23-10-5-3-6-11-23)24-12-7-4-8-13-24/h3-15,26,28H,16-19,21H2,1-2H3
PubChem CID	10098082
ChEMBL	CHEMBL418989
IUPHAR	N/A
BindingDB	50046016
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
ID50	0.083 mg.kg-1	PMID8411016	ChEMBL

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