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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL103287
Molecular formula	C25H31N5O
IUPAC name	2-(2-methylpyridin-3-yl)-2-[4-(3-phenyl-3-pyrrolidin-1-ylpropanoyl)piperazin-1-yl]acetonitrile
Molecular weight	417.557
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.3
Synonyms	SCHEMBL9575212 (2-Methyl-pyridin-3-yl)-[4-(3-phenyl-3-pyrrolidin-1-yl-propionyl)-piperazin-1-yl]-acetonitrile [4-[3-Phenyl-1-oxo-3-(1-pyrrolidinyl)propyl]piperazin-1-yl](2-methyl-3-pyridyl)acetonitrile BDBM50045987
Inchi Key	FYFQQYNMAZJMLD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31N5O/c1-20-22(10-7-11-27-20)24(19-26)29-14-16-30(17-15-29)25(31)18-23(28-12-5-6-13-28)21-8-3-2-4-9-21/h2-4,7-11,23-24H,5-6,12-18H2,1H3
PubChem CID	9979382
ChEMBL	CHEMBL103287
IUPHAR	N/A
BindingDB	50045987
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
90195	Platelet-activating factor receptor	P46002	Ptafr	Rattus norvegicus (Rat)	341
90196	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342

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