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GPCR

NamePlatelet-activating factor receptor
SpeciesRattus norvegicus (Rat)
GenePtafr
SynonymAGEPC receptor
PAF receptor
PAF-R
PAFr
DiseaseN/A for non-human GPCRs
Length341
Amino acid sequenceMEQNGSFRVDSEFRYTLFPIVYSVIFVLGVVANGYVLWVFATLYPSKKLNEIKIFMVNLTVADLLFLMTLPLWIVYYSNEGDWIVHKFLCNLAGCLFFINTYCSVAFLGVITYNRYQAVAYPIKTAQATTRKRGITLSLVIWISIAATASYFLATDSTNVVPKKDGSGNITRCFEHYEPYSVPILVVHIFITSCFFLVFFLIFYCNMVIIHTLLTRPVRQQRKPEVKRRALWMVCTVLAVFVICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFRKHLSEKFYSMRSSRKCSRATSDTCTEVMMPANQTPVLPLKN
UniProtP46002
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4127
IUPHARN/A
DrugBankN/A

Ligand

NameCHEMBL125315
Molecular formulaC38H65NO6S2
IUPAC name3-[6-[(2-heptadecyl-1,3-dioxolan-4-yl)methoxy]hexyl]-4-methyl-1,3-thiazol-3-ium;4-methylbenzenesulfonate
Molecular weight696.059
Hydrogen bond acceptor7
Hydrogen bond donor0
XlogPNone
SynonymsSCHEMBL9873008
Inchi KeyFPVUQJWOEDBVKM-UHFFFAOYSA-M
Inchi IDInChI=1S/C31H58NO3S.C7H8O3S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22-31-34-26-30(35-31)25-33-24-21-18-17-20-23-32-28-36-27-29(32)2;1-6-2-4-7(5-3-6)11(8,9)10/h27-28,30-31H,3-26H2,1-2H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
PubChem CID23042918
ChEMBLCHEMBL125315
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
Partition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
ID503.1 mg.kg-1PMID1992139ChEMBL

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