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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

NameGalanin receptor type 2
SpeciesHomo sapiens (Human)
GeneGALR2
SynonymGAL2 receptor
GAL2-R
GALNR2
GALR-2
DiseaseN/A
Length387
Amino acid sequenceMNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
UniProtO43603
Protein Data BankN/A
GPCR-HGmod modelO43603
3D structure modelThis predicted structure model is from GPCR-EXP O43603.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3176
IUPHAR244
DrugBankN/A

Known ligands

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Total entries: 190
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GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
20172D structureMLS000053810C21H22N2O5382.4165 / 12.7Yes
121632D structureMLS000573994C21H16ClN3O3S425.8874 / 34.8Yes
121652D structureAC1LQ8SVC21H16ClN3O3S425.8874 / 34.8Yes
209652D structureCHEMBL1922021C25H30FN5O2451.5468 / 36.7No
216152D structureCHEMBL524892C97H164N22O201958.5124 / 255.2No
218142D structureCHEMBL1922020C24H28FN5O2437.5198 / 25.7No
5221192D structureCHEMBL3775436C15H26ClNO3303.8274 / 3N/AN/A
5222072D structureCHEMBL3775769C15H26ClNO3303.8274 / 3N/AN/A
229522D structureSMR000220470C18H20N4292.3863 / 24.1Yes
261212D structureCHEMBL1922010C23H26FN5O2423.4928 / 25.3No
271762D structureCHEMBL2203713C18H22N4S326.4624 / 22.9Yes
334912D structureUNII-7W7511NPF8C20H20N2O3S368.4516 / 11.8Yes
372602D structureBDBM34796C16H17NO4S319.3755 / 24.5Yes
381772D structureCHEMBL506553C139H210N42O433157.4648 / 48-15.9No
383352D structureMLS000391056C20H27ClN2OS378.9592 / 14.7Yes
389982D structureMLS000696579C21H24N4O3S2444.5687 / 24.7Yes
436732D structureAC1NVS6HC16H17NO4S319.3755 / 03.3Yes
441002D structureMLS000587374C30H44N2O4496.6926 / 25.2No
484462D structureCHEMBL1210154C19H16N2O2S336.4094 / 14.7Yes
484642D structureSCHEMBL4318956C19H16N2O2S336.4094 / 14.7Yes
504062D structureellipticineC17H14N2246.3131 / 14.8Yes
525152D structureCHEMBL1922023C28H29FN6O2500.5789 / 26.0No
538952D structureGal-B5C101H169N23O212041.625 / 254.7No
544992D structureCHEMBL1922012C23H26FN5O407.4937 / 25.7No
578332D structureCHEMBL1922014C22H23ClFN5O427.9087 / 26.0No
590752D structureCHEMBL1922025C28H35FN6O4538.62410 / 25.5No
592012D structure1,10-phenanthrolineC12H8N2180.212 / 01.8Yes
615472D structureSCHEMBL604437C18H25N5O327.4326 / 21.3Yes
649792D structureCHEMBL503924C51H61N10O11+990.10814 / 74.4No
650032D structureMLS000374746C20H18Cl2N4O4S481.3486 / 02.5Yes
706852D structureGalB2C104H173N23O232113.6727 / 262.9No
711862D structureMLS000394090C18H18N4O3S3434.5478 / 13.2Yes
729182D structureCHEMBL1921996C24H27F2N5O2455.519 / 37.0No
761482D structureCHEMBL1921999C24H26F3N5O2473.510 / 37.2No
786862D structureGalanin-1-16C78H116N20O211669.9123 / 22-2.9No
832532D structureCHEMBL1922004C24H29N5O403.536 / 26.0No
844272D structureCHEMBL503924C53H61F3N10O131103.1220 / 8N/ANo
877592D structure[Sar1Gly]GAL-B2C103H172N24O222098.6626 / 264.0No
5243332D structureSCHEMBL2101506C21H20ClFN2O4418.8495 / 32.3Yes
1084592D structureCHEMBL1922016C24H28FN5O2437.5198 / 25.7No
1193462D structureCHEMBL1922024C28H35FN6O2506.6269 / 25.9No
1218272D structureCHEMBL501306C104H174N24O222112.6826 / 264.6No
1227362D structureCHEMBL1922009C23H25F2N5O2441.4839 / 26.1No
1235032D structureGalanin ratC92H135N27O262035.2629 / 28-6.9No
1238512D structureMLS000588327C20H16N4OS360.4354 / 13.5Yes
1245832D structureSMR000146590C14H14N2O4S306.3365 / 01.9Yes
5539192D structureSNAP-398299C27H24F3N3O2479.5037 / 05.7No
1314312D structureCHEMBL1922007C23H24F3N5O2459.47310 / 26.4No
1317232D structureMLS000584180C18H15ClN2O2326.784 / 13.3Yes
1323032D structure1103458-91-8C29H30N6O3510.5987 / 22.7No
1339462D structureethyl 4-{3-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-2,5-dioxopyrrolidin-1-yl}benzoateC24H25BrN2O5501.3776 / 12.9No
1345792D structureBenzthiazole compound, 33pC21H23N3O3S397.4936 / 23.3Yes
1346822D structureCHEMBL450827C106H177N23O232141.7227 / 256.2No
1355202D structureCHEMBL2309599C40H46N4O6678.837 / 46.5No
1366012D structureCHEMBL1921991C22H24FN5O393.4667 / 25.3No
1374082D structureMLS000096632C16H18N2O5S350.3897 / 11.6Yes
1395372D structureCHEMBL1921998C24H29N5O2419.5297 / 36.0No
1413482D structureCHEMBL1921901C23H27N5373.5045 / 26.0No
1445042D structureCHEMBL1922015C22H24FN5O2409.4658 / 24.9Yes
1495982D structureCHEMBL571758C14H11BrClN3336.6172 / 14.1Yes
1505452D structureCHEMBL1921997C24H26F3N5O2473.510 / 37.2No
1510352D structure2-(2,5-dinitrothiophen-3-yl)pyrimidineC8H4N4O4S252.2047 / 01.9Yes
1568722D structureCHEMBL507353C104H173N23O232113.6727 / 255.1No
1578112D structureCHEMBL1922003C27H31F4N7529.58811 / 16.4No
1579612D structureWTLNSAGYLLC54H80N12O151137.316 / 16-2.1No
1598442D structure(Sar)WTLNSAGYLLGPKKKKC88H143N23O221875.2527 / 25-2.5No
1617422D structureM35 PeptideC107H153N27O262233.5628 / 27-1.8No
1623252D structureMLS000056239C21H22N2O3S382.4784 / 13.3Yes
4482632D structureCHEMBL3334797C15H22Cl2N2O317.2543 / 03.1Yes
1696692D structureCID 25180486C95H150N22O211936.3823 / 235.3No
1716622D structureCHEMBL1921988C22H23F2N5O411.4578 / 26.2No
1719162D structureEPPTBC20H21F3N2O2378.3956 / 14.6Yes
4845092D structureCHEMBL3613642C21H23F3N4O5S500.49310 / 13.2No
1750212D structureCHEMBL1921803C23H25F2N5O2441.4839 / 26.1No
1750682D structureCHEMBL524678C102H169N23O232085.6127 / 254.0No
1754402D structureCHEMBL1922006C23H24F3N5O2459.47310 / 26.4No
1757522D structurebrefeldin AC16H24O4280.3644 / 22.0Yes
1757542D structurebrefeldin AC16H24O4280.3644 / 22.0Yes
1761742D structureCHEMBL2326501C24H33N3O3411.5465 / 25.4No
1788932D structureCHEMBL2324949C93H150N24O211940.3726 / 26-1.6No
1811372D structureethyl 2-(acetylamino)-4,5-dinitrobenzoateC11H11N3O7297.2237 / 11.5Yes
5541922D structuredithiipin-1,1,4,4-tetroxide analogue 7C12H14O4S2286.364 / 01.1Yes
1835672D structureSMR000235764C22H26N4O3S2458.5957 / 25.1No
1837622D structureCHEMBL1922001C28H34F3N7525.62410 / 16.7No
1839612D structureCHEMBL1922002C27H31F4N7O545.58712 / 16.0No
1845192D structureGalanin (3-29), porcineC133H199N39O392968.2945 / 42-11.7No
1867972D structureMLS000068597C15H18N2O2S290.3814 / 12.4Yes
5407922D structureCHEMBL3883366C13H17NO2219.2842 / 21.7Yes
1957382D structureD0D3CGC138H199N35O302828.3233 / 350.5No
1959292D structureCHEMBL1921987C22H22F3N5O429.4479 / 26.4No
2003892D structureMLS000696629C23H28N4O3S2472.6227 / 25.5No
2030642D structureMLS000567024C14H9N3S251.3073 / 13.0Yes
2040442D structureSMR000235775C22H26N4O3S2458.5957 / 25.0Yes
2041452D structureMLS000587374C30H45ClN2O4533.156 / 3N/ANo
2048902D structureCHEMBL1922022C26H27FN8O2502.55411 / 24.7No
2073482D structureCHEMBL505299C99H163N23O282123.5332 / 25-2.9No
2099602D structureCHEMBL507733C100H165N23O232057.5627 / 253.0No
2123512D structureMLS000390375C17H18Cl2N4O3397.2564 / 12.4Yes
2128212D structureCHEMBL525755C104H174N24O222112.6826 / 264.6No
5640392D structureMLS000391275C17H12FN5S337.3766 / 24.8Yes

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